AstraZeneca notches up another PhIII failure as lung cancer trial falls short
AstraZeneca ($AZN) has posted another set of negative numbers for the cancer drug it licensed from Array Biopharma ($ARRY). The latest setback saw the MEK 1/2 inhibitor selumetinib fail to improve either progression-free or overall survival in patients with KRAS mutation-positive non-small cell lung cancer (NSCLC). SELECT-1, the Phase III trial, enrolled 510 patients with locally-advanced or metastatic NSCLC and randomized them to receive either selumetinib or a placebo on top of chemotherapy dr..>> view originalOne drug is 'new hope' for three killer infections
Image copyright Getty Images Image caption A child with leishmaniasis One drug can treat three deadly and neglected infections - Chagas disease, leishmaniasis and sleeping sickness - animal studies show. It has been described as a "new hope" for tackling the parasitic infections which affect millions of people in the poorest parts of the world. The discovery, reported in the journal Nature, was made by testing three million compounds. The new drug is ..>> view originalTough new vaping rules are suffocating e-cig retailers
New federal regulations kicked in Monday for electronic cigarettes and some tobacco-related products, giving the U.S. Food and Drug Administration greater control over what can be sold and limiting the way retailers interact with customers.Such restrictions, however, are nothing new to California’s owners and operators of “vape bars,” where customers gather to smoke e-cigarettes. Two months ago the state launched its own restrictions, including raising the legal age for all smoking from 18 to ..>> view originalCool temperatures, few mosquitoes make Games Zika free, so far
RIO DE JANEIRO – So far, at the Olympics many feared would be the Zika Games, so good. With as many as one million people expected to attend the spectacle, half of them foreigners, Rio de Janeiro has not turned out to be the Zika hothouse some athletes and visitors feared as the virus wreaked havoc in Brazil earlier this year. Despite some hot days, swings back to cooler temperatures in Brazil's winter mean that the population of the mosquito responsible for spreading the virus has dwindled. A..>> view originalObamacare Appears to Be Making People Healthier
Photo Wanda Morrison, 61, of Louisville, Ky., with her physician, Dr. Kimberley Brumleve, at the Family Health Center in Louisville in November 2015. Credit Brittany Greeson for The New York Times Obamacare has provided health insurance to some 20 million people. But are they any better off?This has been the central question as we’ve been watching the complex and expensive health law unfurl. We knew the law was giving people coverage, but information about whether it’s ..>> view originalMesoblast's Stem-Cell Treatment Shows Improvement In Rheumatoid Arthritis Patients
Australia-based regenerative medicine company Mesoblast Ltd. announced Monday that experiments it was carrying out as a part of stem-cell treatment have led to significant improvements of symptoms and disease activity in rheumatoid arthritis patients who were unable to get relief through widely used biotech medicines.Rheumatoid arthritis is a chronic autoimmune disease that is found in about one percent of the world’s population. The disease affects the synovial membrane of multiple joints, even..>> view originalFirst Rio gold medal is within reach for US women's gymnastics at team final
And barring a major disaster, the question heading into the team final Tuesday afternoon at the Rio Olympic Arena won't be whether these five American women will win gold. It will be which teams get silver and bronze behind them.On Sunday, Team USA dominated team qualification. The US led all countries with a total score of 185.238, almost 10 points higher than the second-best team, China (175.279).The US women are also on a winning streak. In addition to winning team gold in London in 2012, Tea..>> view originalOnline marketplace offers cheaper CPAP machines without a prescription
There is a large market for unauthorized online sales of secondhand continuous positive airway pressure (CPAP) devices, which treat obstructive sleep apnea, according to a new study. Purchased from an authorized vendor through a sleep clinic, a CPAP machine can cost $600 to $2,000 for patients with little or no insurance coverage, the authors write. “We did not speak directly with sellers or buyers, so we can only speculate on why this market exists, but we suspect that sellers have CPAP machin..>> view originalVa. bride walked down the aisle by man who got her father's heart
Jeni Stepien of Virginia was walked down the aisle on her wedding day by Arthur Thomas — the man who received her father's heart transplant. (ABC). BY Keri Blakinger. NEW YORK DAILY NEWS. Tuesday, August 9, 2016, 6:31 AM. Her father wasn't there ...>> view originalAmericans are still not worried about Zika, poll finds
A plane sprays pesticide over the Wynwood neighborhood in Miami. The Centers for Disease Control and Prevention has advised pregnant women to avoid travel to this area because Zika virus is spreading to people through mosquito bites. (Joe Raedle/Getty Images) Zika's first mosquito-borne transmission in the United States has not sparked alarm for the vast majority of Americans, who do not fear infection by the disease, according to a new Washington Post-ABC News poll. Sixty-five percent of A..>> view original
Thursday, August 11, 2016
AstraZeneca notches up another PhIII failure as lung cancer trial falls short and other top stories.
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